ASSESSMENT OF SERUM ZINC LEVEL IN CHILDHOOD EPILEPSY TREATED WITH LONG-TERM ANTI EPILEPTIC DRUG (AED

Authors

  • Shamin-Ara Sarkar Holy Family Red Crescent Medical College & Hospital,
  • Habibur Rahman Institute of Health Technology,Mohakhali, Dhaka
  • Israt Jahan Bangladesh University of Health Sciences (BUHS), Mirpur-1, Dhaka,
  • Sharmin Parveen Bangladesh University of Health Sciences (BUHS), Mirpur-1, Dhaka,
  • Md Ranzu Ahmed Bangladesh University of Health Sciences (BUHS), Mirpur-1, Dhaka,

DOI:

https://doi.org/10.51594/imsrj.v1i1.21

Keywords:

Serum Zinc, Childhood, Epilepsy, Antiepileptic Drug, Long-Term

Abstract

Almost 85% of epilepsy patients which is a common neurolotical disease lives in developing world. Mostly the disease start in childhoold in more than half o the cases. Long term use of antiepileptic drugs may alter serum zinc level.   The purpose of the present study was to assess the serum zinc level in childhood epilepsy treated with long-term Anti Epileptic Drug (AED). This cross-sectional study was carried out in the outdoor and indoor patient department of Pediatric neurology, BSMMU during the period from March 2013 to August 2013. Sample size was one hundred, among these fifty were case e.g. epileptic child who had received  anti epileptic drugs (Carbamazepine and/or Valproic acid) for more than three months and fifty werecontrol e.g. newly diagnosed epileptic child, who have not yet received antiepileptic drugs.  In this study, among100 epileptic child, mean serum zinc level in case group was 0.36(±0.20)(µg/ml)and incontrol group was 0.52(±0.26) (µg/ml),which was statistically significant (p<0.05). The use of one drug or multiple drugs in the treatment of epileptic patients has made the significant low serum zinc level.

Published

2019-06-11 — Updated on 2020-06-23

Issue

Vol. 1 No. 1 (2019)

Section

Articles

Copyright (c) 2019 Shamin-Ara Sarkar, Habibur Rahman, Israt Jahan, Sharmin Parveen, Md Ranzu

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Fair East Publishing has chosen to apply for the Creative Common Attribution Noncommercial 4.0 Licence (CC BY) license on our published work. Authors who wish to publish their manuscript in our journal agree on the following terms:
1. Authors retain the copyright and grant us (Fair East Publishing and its subsidiary journals) the right for first publication with the work licensed under a Creative Commons Attribution (CC BY) License which permits others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal. Under this license, author retains the ownership of the copyright of their content, but anyone is allowed to download, reuse, reprint, modify, distribute, and/or copy the contents as long as the original authors and source are cited. No permission is required from the publishers or authors.
2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (for example, publishing it as a book or submitting it to an institutional repository), with an acknowledgment of its initial publication in Fair East Publishing owned journals.
3. We encourage our authors/contributors to post their work online (such as posting it on their website or some institutional repositories) prior to and during the submission process since it produces scholarly exchange and greater and earlier citation of published work.